Where does “-afil” come from?

-afil (English) comes from English sildenafil, from English sulfonyl, from English -yl, from French méthylène, from Ancient Greek μέθυ, from Proto-Hellenic métʰu, from Proto-Indo-European médʰu — honey; honey wine, mead.

-afil (English): Used to form names of inhibitors of phosphodiesterase [[w:cGMP-specific phosphodiesterase type 5

Definitions

  1. Used to form names of inhibitors of phosphodiesterase [[w:cGMP-specific phosphodiesterase type 5

Ancestry of “-afil”, step by step

StepLanguageWordMeaning
1EnglishsildenafilA drug that is used in the form of its citrate C22H30N6O4S·C6H8O7 to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiat
2EnglishsulfonylThe bivalent radical or functional group -SO-;...
3English-ylA univalent radical or functional group formed...
4Frenchméthylènemethylene
5Ancient Greekμέθυwine
6Proto-Hellenicmétʰuintoxicating drink; mead
7Proto-Indo-Europeanmédʰuhoney; honey wine, mead

Words derived from “-afil

Every word from Proto-Indo-European médʰuEvery word from English -ylEvery word from Proto-Hellenic métʰu