Where does “anti-Karen” come from?

anti-Karen (English) comes from English anti, from English anti-, from Ancient Greek ἀντι-, from Ancient Greek ᾰ̓ντῐ́ — opposite.

anti-Karen (English): An individual, usually a woman, who acts with kindness, empathy, and respect towards others

Definitions

An individual, usually a woman, who acts with kindness, empathy, and respect towards others

anti-Karen traces back through two separate lines of ancestry.

Step	Language	Word	Meaning
1	English	anti	Opposed to something; That has a torsion angle...
2	English	anti-	Against, hostile to; Contrasting with the norm;...
3	Ancient Greek	ἀντι-	anti-, against; like, reminiscent of
4	Ancient Greek	ᾰ̓ντῐ́	opposite

Step	Language	Word	Meaning
1	English	Karen	A middle-aged white woman exhibiting a sense of...
2	Danish	Karen	—
3	Danish	Katharina	Catherine