Where does “unsignificance” come from?

unsignificance (English) comes from English significance, from French signification, from Latin significatio, from Latin -tiō, from Latin dissertātiō, from Latin dissertus, from Latin disserere, from Latin dis- — small stone, pebble; gravel, rubble.

Ancestry of “unsignificance”, step by step

StepLanguageWordMeaning
1EnglishsignificanceThe extent to which something matters;...
2Frenchsignificationmeaning; definition; signification
3Latinsignificatiosignal, sign, mark, token; applause; meaning,...
4Latin-tiōtion, -ation, -ing
5Latindissertātiō(spoken) dissertation, discourse, disquisition
6Latindissertusarranged, disposed; explained
7Latindissereresecond-person singular future passive indicative...
8Latindis-asunder, apart, in two; reversal, removal;...
9Latincalceusshoe
10Latincalxlimestone; chalk; the finish line
11Ancient Greekχάλιξsmall stone, pebble; gravel, rubble
Every word from Ancient Greek χάλιξEvery word from Latin -tiōEvery word from Latin dis-