Where does “vacuola” come from?

vacuola (Latin) comes from Latin vacuus, from Latin -uus, from Proto-Italic *-wos, from Proto-Indo-European -wós — Creates adjectives from verb stems.

Ancestry of “vacuola”, step by step

StepLanguageWordMeaning
1Latinvacuusempty, vacant, unoccupied; devoid or free of,...
2Latin-uusforms adjectives on verbal stems
3Proto-Italic*-wos
4Proto-Indo-European-wósCreates adjectives from verb stems
Every word from Proto-Indo-European -wósEvery word from Latin -uusEvery word from Latin vacuus